Contains material gathered or created by Andrews in preparation for creating cartoons or other artwork. This includes clippings of newspapers (often annotated by Andrews), his notes on news items and sketches in pencil. Also included are idea files, which contain a combination of clippings, notes and sketches on particular themes or topics. A small number of sketchbooks and two rolls of sketches are also part of this series.

Most of the material in this series was collected or created while Andrews was employed by the Daily World. As a result, many of the clippings, sketches and notes respond to current events, including the Vietnam War, the Attica Prison riots, and the activities of President Richard M. Nixon, including his resignation.

A small amount of material was also created by Andrews when he worked for Arizona State University. These sketches are for promotional brochures, fliers and posters.

Contains the final versions of Andrews' artwork before it was screened and sized for publication. Most of this artwork consists of single frame pen and ink cartoons, and much of it is oversize.

Most of the material in this series was created while Andrews was employed by the Daily World. As a result, this artwork is largely editorial in nature, responding to current events from the perspective of the Daily World and the Communist Party of the United States of America.

A small amount of material was also created by Andrews when he worked for Arizona State University. This artwork consists of promotional brochures, fliers and posters for the University as a whole as well as specific departments or offices.

Contains the screened and sized versions of Andrews' artwork as prepared for publication. These materials are often touched up in order to achieve the Andrews' desired level of contrast and contrast. Prints he felts were unacceptable were placed in a folder titled "Unusable". Full-size versions of almost all of these prints can be found in the Finished Artwork series of this collection.

Almost all of this material dates from the time that Andrews was employed at the Daily World, and responds to current events from the perspective of the Daily World and the Communist Party of the United States of America.

A very small amount of material was created during the time that Andrews worked for Arizona State University, mostly for sizing purposes.

Contains clippings, correspondence, clippings of Andrews' published artwork, typescripts and topical files assembled by Andrews. Of particular significance are typescripts of Andrews' talks describing his creative process as well as the editorial processes of the Daily World, leaflets and flyers he collected during the 1960s and 1970s, typescripts of articles (including musical album and concert reviews), and materials from his March 1977 trip to Moscow to participate in the Satire in the Struggle for Peace Exhibition. A folder containing photographs of Andrews is also present in the collection. The series also contains an oral history interview with Andrews, taken following the processing of the collection.

Contains ephemeral and three-dimensional objects, including Andrews' camera, awards, printing plates, a scrapbook from his high school years, and an armband from an April 1969 protest against the Vietnam War.

Contains artwork given to Andrews by other artists, including friends such as Homer Kellogg, Marcia Yutman and Marilyn and Charles Trussell as well as professional cartoonists, including Kearny Egerton, Bil Keane and Gee Tee Maxwell, whom Andrews befriended while working at the Arizona Republic. Also included is artwork sent to Andrews while he worked at the Daily World from individuals seeking to have their work published in the paper.