This series contains seven bound volumes and two three-ring binders of minutes from annual and regular meetings of the Hospital's Board of Directors throughout the entirety of the series date range. The minutes offer a detailed overview of the activities that transpired at each meeting, including the presentation of various reports, adoption of recommendations, passing of motions, formation of committees, and appointment of board and committee members.

Predominant subjects recorded in the minutes include the state of the Hospital's finances, detailing income, expenses, funds, and financial campaigns; the management of the Hospital's real estate and mortgages; the activities of the Hospital's Medical Board (later called the Board of Surgeons), largely relating to the appointment of medical staff members; relations between the Board and Hospital employees, often concerning employee salaries; the types of medical services offered by the Hospital; statistics on clinic visits, hospital admissions, and occupancy rates; the condition of various facilities and equipment; the activities and recommendations of the Board's several committees; and the Board's response to the death or resignation of Board members. Minutes dating from the 1930s onward increasingly illuminate the actions taken by the Board in response to the Hospital's financial difficulties, including the attempt to solidify a merger with other medical institutions.

The volumes and binders also include occasional supplementary items relating to the issues discussed by the Board, including correspondence, newspaper clippings, corporate resolutions and trust agreements, full reports of various committees, and brochures related to financial campaigns. The very first volume, covering the period 1868 to 1915, also includes the Hospital's act of incorporation, while the second volume, covering the period 1916 to 1929, includes the Hospital's constitution and bylaws.

The series also includes two four-ring binders containing internal renditions of the Hospital's annual reports, as well as treasurer and superintendent's reports, dating from 1916 to 1929. Annual and treasurer's reports concern the state of the Hospital's finances and are supplemented by comparisons of receipts and expenses, while superintendent's reports relate to patient and medical statistics and are supplemented by comparisons of clinic, hospital, and dispensary work.

An additional folder contains minutes and reports of the Board's Executive Committee, dating from 1919 to 1929. The minutes and reports largely concern the Hospital's finances and real estate, as well as the Hospital's consolidation with the Williamsburgh Hospital. A small portion of the folder is also comprised of minutes and reports of the Board's Building and Plans Committees, which largely detail proposed improvements to the Hospital's floor layouts, equipment, and furnishings, as well as the plans for the Hospital's new building on Greene Avenue. The folder also includes correspondence, reports of inspections conducted by the New York City Department of Public Welfare and the New York State Board of Charities, committee resolutions, trust agreements, and documents related to changes in the Board's constitution and bylaws.

Finally, the series includes a folder housing a copy of the Board's published annual report from 1930, a history and prospectus of the Hospital from 1913, and two copies of the book A Hospital's First Century, written by Board member Harry W. Baehr in commemoration of the Hospital's centennial in 1968.

This series contains six bound volumes and two four-ring binders containing minutes of the annual, regular, and special meetings of the Hospital's Board of Surgeons, which functioned as the governing body for the Hospital's medical staff. In the first two volumes, which cover the period 1926 to 1940, the Board of Surgeons is referred to under its previous name, the Medical Board. The minutes span the entire date range covered by the series and detail the items deliberated upon at each of the Board's meetings, as well as the Board's decisions regarding various aspects of the Hospital's medical operations.

Prominent issues covered in the minutes include the formation of Board committees and auxiliaries; committee recommendations and reports; nominations and appointments of individuals to medical positions; resignations of Board and medical staff members; the management of the Hospital's education initiatives, including its intern and residency programs; the conduct and duties of medical staff and interns; employee salaries; results of clinical trials; acquisition of medical equipment; guidelines and regulations for medical and surgical procedures; the application of various medical drugs, instruments, and practices; medical staff rotations and operative schedules; actions taken by the Board to comply with industry regulations and professional standards; participation among Board members in various professional organizations; and the honoring of deceased Board and medical staff members. Supplementary items relevant to the Board's activities are also included in the volumes and binders, including correspondence, resolutions, full committee and departmental reports, and rules and regulations for medical staff and interns.

The series also contains eight four-ring binders of minutes from meetings of several of the Board's committees throughout the period 1970 to 1975. The committee minutes expound upon the Board minutes of the same period, and offer more specific information on the duties performed by members of the Hospital's medical staff, the governance of the medical staff, the interrelation of the Hospital's medical departments, medical and patient statistics, the disorders and diseases treated by the Hospital, and the applications of medical treatments and surgical procedures. Most of the binders consolidate the minutes of several committees and are organized alphabetically by committee name; however, one binder exclusively contains the minutes of the Committee on Infections, while two binders solely contain the minutes of the Opthalmic Committee. The Ophtalmic committee is also represented by an additional folder of material dating from 1964 to 1974.

Finally, the series also contains one four-ring binder of minutes from meetings of medical deptartment heads during the period 1969 to 1975, and two copies, bound and unbound, of a medical staff manual adopted by the Board of Surgeons in 1971.